EGI Foundation is leading the design of LETHE system architecture and building a data collection and big data framework, including set-up of the LETHE big data infrastructure, set-up the authentication scheme for the LETHE project and registration of the LETHE infrastructure and services in EOSC.
LETHE will provide a novel data-driven risk factor prediction model for older individuals at risk of cognitive decline building upon big data analysis of cross-sectional observational and longitudinal intervention datasets from 4 clinical centers in Europe including the 11-years analysis of FINGER. LETHE will establish novel digital biomarkers, for early detection of risk factors, based on unobtrusive ICT-based passive and active monitoring.